CRISPR and beyond – perturbations at scale to understand genomes

02 – 04 September 2019, Wellcome Genome Campus, UK

Registration is now open for CRISPR and Beyond: Perturbations at Scale to Understand Genomes. The rapid advances of CRISPR/Cas-based technologies and DNA synthesis now make it possible to modulate genomes with relative ease. These tools can help us understand how genetic variation impacts phenotype and answer important long-standing questions in biology that also impact human health, laying the foundations for precision medicine for heritable diseases and cancer treatment. This conference will bring together biomedical researchers working on high throughput screening, genome engineering, and/or variant effect interpretation, to explore these advances. Early Bird discount is available until 11 June 2019. A limited number of bursaries are available for PhD students to attend the meeting. Please feel free to forward this message on to colleagues who may also have an interest in this conference. Scientific sessions include: Understanding impact of coding variants Measuring consequences of non-coding variation Screens for gene function in cells Assaying gene function in organisms Gene and drug function in disease Interactions with genes, drugs, and environment New technology for readouts and perturbations

SCIENTIFIC PROGRAMME COMMITTEE John Doench Broad Institute of MIT and Harvard, USA   Jolanda van Leeuwen University of Lausanne, Lausanne, Switzerland   Leopold Parts Wellcome Sanger Institute, UK   Lea Starita University of Washington, USA

CONFIRMED SPEAKERS Brit Adamson University of Princeton, USA Brenda Andrews University of Toronto, Canada Michael Boutros DKFZ Heidelberg, Germany Ellen Bushell Umea University, Sweden Ulrich Elling Institute of Molecular Biology, Austria Douglas Fowler Unversity of Washington, USA Molly Gasperini University of Washington, USA Maya Ghoussaini Open Targets, UK     Luke Gilbert UCSF, USA Emma Haapaniemi University of Oslo, Norway Ben Lehner Centre for Genomic Regulation, Spain James McFarland Broad Institute, USA Fritz Roth University of Toronto, Canada Jussi Taipale University of Cambridge, UK Sibylle Vonesch EMBL, Germany Yanli Wang Institute of Biophysics CAS, China

Poster: https://coursesandconferences.wellcomegenomecampus.org/wp-content/uploads/2018/12/CRISPR_2019_A4_Poster.pdf