Cell Res. 2022 May 30. doi: 10.1038/s41422-022-00670-6. Online ahead of print.

Maternally loaded RNAs: no time to die

Martino Ugolini ¹, Nadine L Vastenhouw ²

Upon fertilization, the animal genome is often inactive and development is driven by proteins and transcripts that are stored in the egg during oogenesis. In a recent Cell Research paper, Shi et al. show that the RNA helicase Ddx3xb facilitates the translation of stored transcripts in zebrafish embryos by a phase separation-dependent process.

• PMID: 35637270
• DOI: 10.1038/s41422-022-00670-6