A postdoctoral research position is available in the laboratory of Dr. Robert Schneider at the NYU Grossman School of Medicine. The position is focused on translational regulation of T cell development and function, particularly immune suppression by regulatory T cells in breast cancer.

Our laboratory investigates translational regulation in the regulation of breast cancer metastasis, as well as the development and function of different T cell types (https://med.nyu.edu/faculty/robert-j-schneider).

Qualified applicants will join a highly collaborative, supportive, collegial and well-funded research team in the Alexandria Center for Life Sciences, in a state-of-the-art spacious modern laboratory. We use a variety of approaches in our research, including molecular biology, biochemistry, tissue culture, animal and human tissue studies, and new therapeutics development. NYU Grossman School of Medicine is one of the top research institutions in the U.S. and provides a stimulating scientific and intellectual environment with outstanding core facilities, highly interactive and multi-disciplinary faculty, sponsored housing and competitive salaries that well exceed NIH guidelines.

Candidates should have a PhD or MD degree with a strong background in molecular biology. Some background in immunology and animal tumor models would be beneficial. We are seeking candidates that are highly motivated, ambitious, and interested in joining a highly collaborative and productive research group.

Qualified candidates should email their curriculum vitae, a brief letter of research interests and contact information for three references to Robert.schneider@nyulangone.org.

NYU Langone Health/NYU Grossman School of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, military and veteran status, genetic information or any other factor which cannot lawfully be used as a basis for an employment decision.

>>>>> Clic here to read the complete job offer <<<<<

System specialist

Your mission :
Integrate into our team, implement and maintain computer software for the collection, organization, analysis and visualization of *-omics, imaging and/or other data from the fields of life sciences (biology, biomedical research, etc.), and participate to the analysis and visualization of these data in the framework of research projects.

Main duties and responsibilities include :

• Organize, analyze and visualize data; design, implement and/or deploy software; provide analysis results for research projects conducted at BIƆC
• Evaluate and compare means and methods to organize, analyze and visualize data handled at BIƆC

Your profile :

• Master degree in a scientific domain such as computer science, bioinformatics, biology, physics, mathematics, data-science
• Demonstrated capacity to plan, design, implement, deploy and document software projects using at least 1 compiled language and 1 interpreted/scripted language
• Excellent communication skills, in oral and written forms, in French and English
• Candidate CH or EU

Start date : As soon as possible
Term of employment : Fixed-term (CDD)
Work rate : 80 – 100%%

>>>>> Clic here to read the complete job offer <<<<<
Deadline to apply: Feb. 2, 2023

Presentation

In order to complete our team, the UNIL-EPFL Bioinformatic Competence Center (BIƆC) of the Lausanne University is looking for a bioinformatician

Job information

Expecting Starting date: as soon as possible
Contract length : one year, renewable
Activity rate : 80-100%
Workplace : Dorigny, UNIL-Sorge, Génopode building

Web site of the center : https://bix.unil.ch/

Your responsibilities

You will be required to:

• Be in charge of analysis of *-omics,  imaging and/or cytometry data to help researchers find leads and answers in their research.
• Implement, adapt, compare and use informatic tools for these analyses
• Use the clusters and IT infrastructures of UNIL and EPFL to perform the analyses
• Document and report your work and analyses with reproducibility in mind

Your qualifications

We are looking for a person with the following profile:

You have a doctorate in a scientific field (biology, medicine, physics, bioinformatics, computational biology, image analysis).

• Extensive experience in the analysis of *-omics and/or imaging data and understanding of the underlying biological phenomena
• Extensive experience in the use of computer tools and programming in the field of bioinformatics; excellent command of the use of UNIX and computing clusters.
• Creative in the search for solutions, rigorous, reliable, organized and ready to integrate our Center.
• Communicating easily in French and/or in English
• Self-motivated, able to work independently and as a team member

Motivated, independent, enthusiastic to be part of an international and interdisciplinary work environment and to help develop our interinstitutional Center.

The Patrick Aloy lab (IRB Barcelona) believes that AI has the potential to transform drug discovery, as it is reshaping other areas of science and technology. However, to enable systems pharmacology, we need to blend biology and chemistry, and format it in a way that is amenable for modern machine learning. Small molecule bioactivity descriptors (Duran-Frigola et al. Nat Biotechnol 2020; Bertoni et al. Nat Commun 2021) and biological embeddings (Fernández-Torras et al. Nat Commun 2022) may help generalize this approach, smoothing the future transition from precision to personalized medicine. Indeed, we are now working on signature-based generative models where, instead of looking for the most suitable approved drug to treat a patient, we will design specific drugs for each molecular profile.

Please, find below three offers to work in my lab as Research Associate (i.e. senior researchers with an open contract), Postdoctoral Fellow and Research Assistant.

Research Associate:
https://recruitment.irbbarcelona.org/jobs/2298129-research-associate-on-biological-data-science-ref-pd-22-36

Postdoc:
https://recruitment.irbbarcelona.org/jobs/2298216-postdoctoral-fellow-on-systems-medicine-ref-pd-22-37

Research Assistant:
https://recruitment.irbbarcelona.org/jobs/2298188-research-assistant-on-computational-biology-ref-lab-22-28

 Imagine Call for Group Leaders 

Institut Imagine (Institute for Genetic Diseases) is inviting applications for group leader positions in multiple fields corresponding to already existing integrated clinical and scientific programs. Applications should be submitted to the Imagine Executive Committee by December 16th, 2022. Imagine Scientific Advisory Board interviews will then be scheduled in February 2023. 

Why join Institut Imagine? 

Institut Imagine, on the Necker Sick Children Hospital campus in Paris, is an interdisciplinary biomedical research centre, providing excellent core facilities for genomics, cell imaging, and bioinformatics together with creating animal models of human disease (mice, Zebrafish, and Drosophila). Additionally, Imagine strongly emphasizes translational aspects and innovative therapeutic options, including gene therapies. Imagine, supported by a private Foundation, is affiliated with Université Paris Cité, INSERM (French national institute for medical research) and the greater Paris Public Hospitals Group (Assistance Publique-Hôpitaux de Paris). 

As a research and healthcare Institute, Imagine focuses on a wide variety of genetic diseases, studying all aspects of from basic research to translational medicine with an ultimate aim of developing new approaches to therapy including gene therapy and gene editing. The Institute includes over 600 staff members in 28 laboratories organized in integrated care and research programs addressing genetics, immunology and infectious diseases, haematology, nephrology, developmental defects, neurosciences and bioinformatics. All groups address these issues with wet lab, computational approaches, or both. Their projects are deeply entangled with clinical units and referral centres for rare diseases affiliated to the institute. 

A call for applications in four fields 

The Imagine Institute is inviting applications for group leader positions in the following fields corresponding to already existing integrated clinical and scientific programs: 

• • Pathophysiology and biotherapies of genodermatoses / Gene and cell therapy in rare genetic skin diseases (including epidermolysis bullosa), interplay between skin and immune systems in rare and frequent inflammatory skin diseases (psoriasis, Netherton syndrome, Darier disease, …) 
• • Molecular and physiopathological bases of osteochondrodysplasia / Multiomics approaches to characterize the genetic bases of skeletal dysplasia, generating cellular and mouse models, primary cilia, proteoglycan, TGFβ signallings, novel therapeutic approaches. 
• • Genetics of Mitochondrial Disorders / Disease gene identification using omics technologies, pathophysiology and deciphering disease mechanisms, evidence-based clinical trials in mitochondrial diseases, gene therapy of Friedreich ataxia and POLG-related diseases. 
• • Genetics of the intestinal barrier / Implementing cutting-edge approaches towards molecular characterization and therapeutic approaches in paediatric and adult cohorts of severe intestinal disorders with genetic bases. 

Appointments will be made at a junior or senior level, depending on experience. 

Our most important criteria for recruitment are an excellent scientific background, an innovative research proposal, and the opening to translational research. 

Lab spaces, access to bio-collections and data-science centre, access to all Imagine and Necker core facilities, and funding support for the group leader positions (ahead of academic recruitment), will be guaranteed for 4 years, plus, 1 more year, upon SAB evaluation. 

Recruitment procedure 

Applications should be submitted to the Imagine Executive Committee at newgroups@institutimagine.org and must include: 

• • A full CV, including a list of publications and grants obtained 
• • Past and current research achievements and interests (2 pages) 
• • Future research proposals (5 pages max) 
• • Name and addresses of three referees for possible recommendation letters 

Further information will be found on : https://www.institutimagine.org/en/institut-imagine-calling-applications-group-leader-positions-1411

Applications must be received by December 16th, 2022 midday (UTC+2). 

Imagine Scientific Advisory Board interviews for group leader positions will then be scheduled in February 2023. 

Pour compléter son équipe de management, le département d’oncologie (DO) situé sur la cité hospitalière (Agora) est à la recherche d’une assistante ou d’un assistant Lab manager.

Lien vers l’annonce sur le site de recrutement de l’UNIL: https://career5.successfactors.eu/career?career%5fns=job%5flisting&company=universitdP&navBarLevel=JOB%5fSEARCH&rcm%5fsite%5flocale=fr%5fFR&career_job_req_id=20590&selected_lang=fr_FR&jobAlertController_jobAlertId=&jobAlertController_jobAlertName=&browserTimeZone=Europe/Budapest&_s.crb=CpetDXFIgP3%2b75QpV%2f1R%2f8x1VS1WA5Dk9PyUVzI%2fp7k%3d

Informations liées au poste

Entrée en fonction : à convenir
Durée du contrat : CDI
Taux d’activité : 50%
Lieu de travail : Lausanne

Vos activités

Dans vos activités, vous serez amené(e) à :

• Procéder à la gestion du suivi des inventaires du DO
• Éliminer les produits/équipements qui ne sont plus utilisés/obsolètes en respectant les procédures d’élimination
• Création, suivi et maintien des bases de données via FileMaker Pro18 nécessaire à la gestion du DO
• Remplacement ponctuel du logisticien chargé de la commande des produits « hors-stock » effectuées par les groupes de recherche du DO
• Appui aux Lab Managers du DO dans la gestion des projets liés aux infrastructures du DO
• Gestion courante des infrastructures
• Aide la gestion des besoins en réparations des équipements et des infrastructures des laboratoires
• Assurer la responsabilité technique des instruments communs des laboratoires du DO

Votre profil

Nous sommes à la recherche d’une personne avec les compétences suivantes : 

• CFC laboratin(e) ou équivalent
• Bonne connaissance de FileMaker Pro16 ou 18
• Aisance à gérer les bases de données
• Très bonne communication à l’oral et à l’écrit en français
• Niveau B2 en anglais requis
• Flexibilité pour gérer plusieurs projets en parallèle et s’adapter à l’évolution des priorités
• Excellentes compétences organisationnelles et capacité à définir et à atteindre des objectifs analytiques en collaboration avec les collègues et le responsable du laboratoire.
• Bonne communication avec son environnement de travail