EBioMedicine.: co-auth.: B.Thorens (INNODIA Consortium)

EBioMedicine. 2023 May 22;92:104625. doi: 10.1016/j.ebiom.2023.104625.

Gene expression signature predicts rate of type 1 diabetes progression

Tomi Suomi¹, Inna Starskaia², Ubaid Ullah Kalim¹, Omid Rasool¹, Maria K Jaakkola¹, Toni Grönroos¹, Tommi Välikangas¹, Caroline Brorsson³, Gianluca Mazzoni³, Sylvaine Bruggraber⁴, Lut Overbergh⁵, David Dunger⁴, Mark Peakman⁶, Piotr Chmura³, Søren Brunak³, Anke M Schulte⁷, Chantal Mathieu⁵, Mikael Knip⁸, Riitta Lahesmaa⁹, Laura L Elo¹⁰; INNODIA Consortium

Abstract

Background: Type 1 diabetes is a complex heterogenous autoimmune disease without therapeutic interventions available to prevent or reverse the disease. This study aimed to identify transcriptional changes associated with the disease progression in patients with recent-onset type 1 diabetes.

PMID: 37224769
DOI: 10.1016/j.ebiom.2023.104625