New human genome research aids understanding of disease
Los Angeles Times – Il y a 17 heures
But the information assembled by ENCODE research — which shows that regions of the genome once thought to be junk are actually stuffed with DNA “switches” that help direct genes in their work — may help change that, scientists involved with the …
‘Dance of DNA’ performed to celebrate big genome project
Los Angeles Times – Il y a 12 heures
The volume of information produced from the effort (called ENCODE) was huge: Ewan Birney, the British scientist who coordinated analysis, estimated that it’d fill a poster 30 kilometers long and 16 meters high, as we note in our story. Birney told us he tried …
ENCODE’s ‘junk DNA’ claims spark biological bunfight
Register – Il y a 13 heures
It started with this item, “An integrated encyclopedia of DNA elements in the human genome”, which makes the startling claim that the ENCODE project (Encyclopedia of DNA Elements) had data which “enabled us to assign biochemical functions for 80% of …
What Is ENCODE, and Why Does It Matter?
LiveScience.com – Il y a 14 heures
A giant leap has just been taken in humanity’s understanding of itself. That leap is called ENCODE. Here’s what you need to know. Eleven years ago, scientists sequenced the human genome. That is, they unraveled the spirals of DNA packed inside the …
ENCODE project sheds light on human DNA and disease
Los Angeles Times – 5 sept. 2012
More than 400 scientists have conducted upward of 1,600 experiments over five years to produce the Encyclopedia of DNA Elements, which goes by the nickname ENCODE. If graphically presented, the data it has generated so far would cover a poster 30 …
ENCODE Data Describes Function of Human Genome
Bioscience Technology – Il y a 17 heures
The Human Genome Project produced an almost complete order of the 3 billion pairs of chemical letters in the DNA that embodies the human genetic code — but little about the way this blueprint works. Now, after a multi-year concerted effort by more than …
Fighting about ENCODE and junk
Nature.com (blog) – Il y a 13 heures
On Wednesday, a handful of journals including this one released more than 30 papers describing results from the second phase ofENCODE: a consortium-driven project tasked with building the “ENCyclopedia Of DNA Elements,” a manual of sorts defining …
Gigantic New Study Changes Everything We Knew About Human Genes
Business Insider – 5 sept. 2012
The results of a gigantic biology project — called ENCODE — were released today. The project covered ten years of effort by over 400 scientists and has culminated in 30 scientific papers published today. The estimated price of the project, mostly funded by …
Human Genome Encyclopedia, ENCODE, Reveals Complexities Of DNA, Genes
Huffington Post – 5 sept. 2012
The studies come from a $196 million project called the Encyclopedia of DNA Elements, or ENCODE, whose goal is to take the babel produced by the human genome project – the sequence of 3.2 billion chemical “bases” or “letters” that constitute the human …
International Consortium Uses ENCODE To Work Out DNA Role In Disease
RedOrbit – Il y a 22 heures
The Encyclopedia of DNA Elements (ENCODE) is a five-year genetics project involving more than 440 researchers working in 32 labs around the world. The result of this team’s work, which highlights the functionality of what was previously thought to be ‘junk …
CNIO participates in the ENCODE project: A stride forward in biomedical research
Science Codex – Il y a 17 heures
The international Encode project, a collaborative study bringing together hundred of scientists from all round the world, including researchers working at the Spanish National Cancer Research Centre (CNIO), published results yesterday mapping the control …
Inside the Mysterious Dark Matter of the Human Genome
Popular Science – Il y a 16 heures
A five-year project called ENCODE, for “Encyclopedia of DNA Elements,” found that about 80 percent of the human genome is biologically active, influencing how nearby genes are expressed and in which types of cells. It’s not junk DNA, which was previously …
New DNA Encyclopedia Attempts to Map Function of Entire Human Genome
Wired – 5 sept. 2012
A torrent of new data charts the human genome in unprecedented detail, a landmark accomplishment compared by some scientists to the genome’s sequencing in 1999. Hundreds of thousands of new genomic pieces, catalogued for the very first time, are …
DNA project interprets ‘book of life’
CNN – 5 sept. 2012
The project is called the Encyclopedia of DNA Elements (ENCODE). When the Human Genome Project sequenced the human genome in 2003, it established the order of the 3 billion letters in the genome, which can be thought of as “the book of life.” …
Scientists Unveil New Blueprint Of How The Human Genome Works
Hartford Courant – Il y a 22 heures
“It is like opening a wiring closet and seeing a hairball of wires,” said Mark Gerstein, an Encode researcher from Yale told the New York Times. “We tried to unravel this hairball and make it interpretable.” Topics · Science · Medical Research · DNA; See more …
Scientists Unveil ‘Google Maps’ For Human Genome
NPR (blog) – 5 sept. 2012
“We like to think about the ENCODE maps similarly,” said Elise Feingold at the National Human Genome Research Institute.”It allows researchers to look at the chromosomes and then zoom into genes and even down to individual nucleotides in the human …
Researchers: ‘Junk’ DNA plays major role in disease
USA TODAY – 5 sept. 2012
Released Wednesday, the $288 million Encyclopedia of DNA Elements (ENCODE) project was funded by the federal National Human Genome Research Institute over the last five years. It includes reports by 440 researchers from 32 labs worldwide.
Analysis debunks concept of ‘junk DNA’
The Seattle Times – Il y a 14 heures
Dr. John A. Stamatoyannopoulos, associate professor of genome sciences and medicine at the University of Washington, director of the UW Encodecenter, and a senior author on seven Encode-related papers, said understanding how genes turn on and off is …
Bits of Mystery DNA, Far From ‘Junk,’ Play Crucial Role
New York Times – 5 sept. 2012
“Most of the changes that affect disease don’t lie in the genes themselves; they lie in the switches,” said Michael Snyder, a Stanford University researcher for the project, called Encode, for Encyclopedia of DNA Elements. And that, said Dr. Bradley Bernstein, …
A masterful introduction to ENCODE, one of the most impressive genome …
io9 – 5 sept. 2012
Known formally as the “Encyclopedia of DNA Elements,” ENCODE today published 30 papers across three different scientific journals, all with the aim of, as Yong puts it, moving us from “here’s the genome” (the maxim, if you will, of the Human Genome …
ENCODE project: In massive genome analysis new data suggests ‘gene …
Medical Xpress – 5 sept. 2012
As part of a huge collaborative effort called ENCODE (Encyclopedia of DNA Elements), a research team led by Cold Spring Harbor Laboratory (CSHL) Professor Thomas Gingeras, Ph.D., today publishes a genome-wide analysis of RNA messages, called …
The 5-Year, $288-Million-Dollar ENCODE Genome Project Is Completed (VIDEO)
Latinos Post – Il y a 11 heures
After a massive five-year, $288 million effort, scientists have published a study detailing the complex relationship between regulatory proteins, RNA, and gene expression. The human genome was officially completed back in 2003 and revealed that only about …
Data analytics key to leveraging ENCODE DNA project discoveries
FierceHealthIT – Il y a 18 heures
“Now that we have the switches, we can start to understand why a combination of DNA variants might increase the chances of a particular disease,” Harvard pathologist ENCODE researcher Dr. Bradley Bernstein told the newspaper. Data analytics will play a …
ENCODE project: Researchers catalogue functional elements of the genome
Medical Xpress – 5 sept. 2012
Characterizing these switches is one of many goals of the ENCODE project – a sweeping, international effort to create a compendium of all of the working parts of the human genome that have not been well studied or well understood. The function of the vast …
ENCODE project: Yale team finds order amidst the chaos within the human …
Medical Xpress – 5 sept. 2012
The massive Encyclopedia of DNA Elements (ENCODE) unveiled Sept. 5 reveals a human genome vastly more rich and complex than envisioned even a decade ago. In a key supporting paper published in the journal Nature, the lab of Yale’s Mark Gerstein, …
Junk No More: ENCODE Project Nature Paper Finds “Biochemical Functions for …
Discovery Institute – 5 sept. 2012
A groundbreaking paper in Nature reports the results of the Encyclopedia of DNA Elements (ENCODE) project, which has detected evidence of function for the “vast majority” of the human genome. Titled “An integrated encyclopedia of DNA elements in the …
Mystery DNA Is Not ‘Junk’ DNA It’s A Control Panel
PlanetSave.com – Il y a 12 heures
“Just as the Human Genome Project revolutionised biomedical research, ENCODE will drive new understanding and open new avenues for biomedical science. Led by the National Genome Research Institute (NHGRI) in the US and the EMBL-European …
Encode study debunks ‘junk DNA’ theory
Wired.co.uk – Il y a 21 heures
The Encode project has discovered that 80 percent of the human genome has a biochemical function, debunking the theory that non-coding genes are simply “junk DNA”. The Encyclopedia Of DNA Elements project, which was launched in 2003 to pick up …
Global Science Consortium Hails Completion of Massive $288 million Effort to …
HealthNewsDigest.com – Il y a 15 heures
The completion of the project, known as the Encyclopedia of DNA Elements, or ENCODE, announced Sept. 5 with the simultaneous publication of 30 papers in three journals: Nature, Genome Biology and Genome Research. Six review articles will also …
DNA ‘switches’ discovery rests on HudsonAlpha Institute work (video)
al.com (blog) – 6 sept. 2012
HudsonAlpha View full sizeDr. Rick Myers, president and director at HudsonAlpha, and Dr. Chris Gunter talk about the research project is called ENCODE during a press conference at Hudson Alpha Institute for Biotechnology Sept., 2012 in Huntsville, Ala.