Methods Mol Biol.: auth.: C.Dessimoz

Methods Mol Biol. 2017;1446:25-37.

Primer on the Gene Ontology.

Gaudet P1,2Škunca N3,4,5Hu JC6Dessimoz C7,8,9,10,11.


The Gene Ontology (GO) project is the largest resource for cataloguing gene function. The combination of solid conceptual underpinnings and a practical set of features have made the GO a widely adopted resource in the research community and an essential resource for data analysis. In this chapter, we provide a concise primer for all users of the GO. We briefly introduce the structure of the ontology and explain how to interpret annotations associated with the GO.


Annotation evidence; Annotations; Evidence codes; Function; GO files; Gene Ontology structure; Gene association file (GAF); Vocabulary

PMID: 27812933