Bienvenue Aymeric Masson !!!

Hello everyone,

I’m Aymeric Masson, new postdoc in the group of Prof. Alexandre Reymond. I come from Clermont-Ferrand (France), where I did my bachelor’s degree in Life sciences followed by a master’s in Biology and Health with a final internship at iGReD (Institute of Genetics, Reproduction and Development) under the guidance of Dr C. Barrière. During these years, I developed a growing interest in genetics, epigenetics and the bioinformatic aspects that enable the study of these fields.

I moved to Dijon (France) for my PhD which I did in the Génétique des Anomalies du Développement laboratory (GAD) under the supervision of Dr A. Vitobello. During my PhD, I investigated the pathology of variants of uncertain significance mainly by generating transcriptomic data, setting up a chromosome conformation capture (Hi-C) protocol and building a basic skill set for analyzing both types of data. I am delighted to join the CIG to further explore how the genome functions, expresses itself, and the impact of its variations on health.

Aside from sciences and to share a bit about myself, I enjoy playing ice hockey for fun, listening to techno-inspired music (Vitalic, Worakls, Paul K, NTO, Contrefaçon…) and spending time with family and friends. I look forward to meeting and collaborating with all of you, see you around!

CIG Progress Reports 2024-2025

Dear all, 

Please join us for the CIG Progress Reports 2024/2025 seminar series in which we’ll get to hear 30 stories developing in the department.

All are welcome!

Place: Amphimax 412 until early 2025, thereafter GEN auditorium. We will inform you of the room in every reminder email sent before the seminar.

Each speaker presents their work in 20-25 min + 5-10 questions.
For more dynamic discussions, we usually interrupt speakers with questions during the talk. The aim is to share your work with your colleagues and receive scientific feedback.

Please keep in mind that the CIG is very diverse and many of your colleagues are not familiar with details of your field and specific methodologies. Thus, we advise you to balance the amount of presented data against the time you have to present. 

Optional feedback on presentation skills using a questionnaire By popular demand, but only if desired, presenters can receive tips from a couple of PIs to improve presenter skills. For this, we prepared a feedback questionnaire to be filled out together over a brief discussion at the end of the seminar.

Schedule

October 3 at 3:30 p.m. (4:00 p.m. as usual)

CIG Seminars Fall 2024 program

Monday 12:15, Génopode, auditorium B

Monday September 23, 2024
Chloé Zubieta,
CNRS, Laboratoire de Physiologie Cellulaire et Végétale, Grenoble (FRA)
«Getting in phase- ELF3 phase transitions as a molecular mechanism of temperature sensing in Arabidopsis»
Host: Christian Fankhauser

Monday September 30, 2024
Alvaro Rada Iglesias,
University of Cantabria, Santander (ESP)
«Insulation of developmental loci: CTCF can not do it all»
Hosts: PhD Students and Postdocs

Monday October 7, 2024
Seminar on Equality, Diversity & Inclusion
Host: Frédéric Preitner

Monday October 28, 2024
Daan Noordermeer,
Université Paris-Saclay, Institute for Integrative Biology of the Cell, Gif-sur-Yvette (FRA)
«Decrypting genomic insulators in mammalian cells: control of inter-TAD loops through distinctly different mechanisms»
Hosts: Maria C. Gambetta & Nadine Vastenhouw

Monday November 11, 2024
Kiran Padmanabhan,
ENS Lyon (FRA)
«A clockless state: impact on chromatin and transcriptome landscapes»
Host: Paul Franken

Monday November 18, 2024
Annika Nichols,
University of Basel, Biozentrum (CH)
«TBA»
Host: Richard Benton

Thursday November 21, 2024 – CIG/DBMV seminar
Liam Dolan,
Gregor Mendel Institute of Molecular Plant Biology, Vienna (AUT)
«Light-modulated polarity development in Marchantia»
Host: Christian Fankhauser

Monday November 25, 2024
Antoine Peters,
Friedrich Miescher Institute, Basel (CH)
«Mechanisms of intergenerational epigenetic inheritance driving mouse embryonic development»
Host: Nadine Vastenhouw

Monday December 9, 2024
Tsutomu Suzuki,
University of Tokyo (Japan)
«Expanding world of tRNA modifications in health and disease»
Host: Jean-Yves Roignant

Monday December 16, 2024
Sophie Caron,
The University of Utah, Salt Lake City (USA)
«TBA»
Host: Richard Benton

PhD positions at Max Planck, deadline 17.10.2024

https://www.imprs-lm.mpg.de/index.php/join/apply

Applications to the IMPRS-LM PhD program are possible only via our ONLINE PORTAL.

The entire process, from opening of our application portal to the onsite interviews, unfolds over a four-month duration.
Applicants are initially granted a window of 6-8 weeks to register on our portal and complete their application.
Subsequently, our coordination office and the recruiting faculty will evaluate and select the top applicants that will be invited for a first interview online.

The online interviews will consist of two short online interactions: a panel interview & a scientific presentation.
Successful candidates will then be invited to an onsite visit 8 weeks later to meet the recruiting labs and find the best matching projects.

For more information, check the application FAQs or contact us.

WINTER SELECTION 2025

  • online registration and application*: starting on 5 September 2024
  • deadline for application: 17 October 2024
  • deadline for submission of reference letter: 23 October 2024 (24:00 German time)
  • online interviews: 4 – 6 December 2024
  • onsite visit: 3 -5 February 2025

RECRUITING GROUPS

Erdmann LAB
BIOCHEMISTRY / PROTEIN TARGETING / MOLECULAR CELL BIOLOGY / ORGANELLE BIOGENESIS


Kliza LAB
BIOCHEMISTRY / MOLECULAR BIOLOGY / PROTEOMICS / ADP-RIBOSYLATION


Meyer LAB

CELL BIOLOGY / MEMBRANE DYNAMICS / CHEMICAL AND GENETIC PERTURBATIONS / FLUORESCENCE MICROSCOPY


Musacchio LAB

BIOCHEMISTRY / BIOPHYSICS / CELL BIOLOGY / MOLECULAR BIOLOGY


Pfander LAB

CELL BIOLOGY / DNA REPLICATION / IN CELL RECONSTITUTION / GENETIC ENGINEERING


Saccá LAB

SYNTHETIC BIOLOGY / NANOMATERIALS AND SUPRAMOLECULAR CHEMISTRY / SPATIAL ORGANIZATION / DNA NANOTECHNOLOGY


Summerer LAB

SYNTHETIC BIOLOGY / EPIGENETICS and CHROMATIN / DIRECTED EVOLUTION / EPIGENOMICS TECHNOLOGIES


Tatzelt LAB

BIOCHEMISTRY / NEURODEGENERATIVE DISEASES / PROTEIN STRUCTURE AND FUNCTION / FLUORESCENCE MICROSCOPY


Trappmann LAB

BIOMATERIALS / TISSUE ENGINEERING / CELL-MATRIX INTERACTIONS / 3D CELL CULTURE


Westermann LAB

BIOCHEMISTRY / CELL BIOLOGY / CYTOSKELETON / CELL DIVISION: MITOSIS AND MEIOSIS


Winklhofer LAB

Project 1: CELL BIOLOGY / CELL SIGNALING / HOST PATHOGEN INTERACTIONS / LIVE CELL IMAGING
Project 2: BIOCHEMISTRY / NEURODEGENERATIVE DISEASES / PROTEOSTASIS / POST-TRANSLATIONAL MODIFICATIONS

NEXT SELECTION SUMMER 2025

  • online registration and application*: March-April 2025
  • online interviews: May 2025
  • onsite visit: June/July 2025

*By submitting your application to the IMPRS-LM database you allow us to store and process your data exclusively for the purpose of the recruitment process.
Please read here the Data Protection Statement of the IMPRS-LM.

Protein Sci, co-auth.:A.Stasiak

Theta-curves in proteins

Pawel Dabrowski-Tumanski 1Dimos Goundaroulis 2 3Andrzej Stasiak 4 5Eric J Rawdon 6Joanna I Sulkowska 7

. 2024 Sep;33(9):e5133.

  • PMID: 39167036
  • PMCID: PMC11337915 (available on 2025-08-21)
  • DOI: 10.1002/pro.5133

Abstract

We study and characterize the topology of connectivity circuits observed in natively folded protein structures whose coordinates are deposited in the Protein Data Bank (PDB). Polypeptide chains of some proteins naturally fold into unique knotted configurations. Another kind of nontrivial topology of polypeptide chains is observed when, in addition to covalent bonds connecting consecutive amino acids in polypeptide chains, one also considers disulfide and ionic bonds between non-consecutive amino acids. Bonds between non-consecutive amino acids introduce bifurcation points into connectivity circuits defined by bonds between consecutive and nonconsecutive amino acids in analyzed proteins. Circuits with bifurcation points can form θ-curves with various topologies. We catalog here the observed topologies of θ-curves passing through bridges between consecutive and non-consecutive amino acids in studied proteins.