This Thursday (July 15) at 9.30, Johanna Gassler will give a talk entitled “Chromatin reorganization to totipotency during the mammalian oocyte-to-zygote transition” in Génopode auditorium B.
Johanna is a postdoc candidate for the Vastenhouw lab and she has done some exciting work on the oocyte to zygote transition in mouse embryos during her PhD in the lab of Kikue Tachibana at the IMP in Austria.
We can host 28 people in the auditorium and there might be about 10 slots left, so please feel welcome to join in person. We will also broadcast the talk on zoom for those who cannot be here.
We are looking for a postdoc to apply for a new call, recently released in Spain with the NEXT European funds. Briefly, we look for a postdoc to work in (Epi)Genomics of Complex Diseases and Childhood Development, with skills in:-Bioestatistis/Bioinformatics/Epidemiology-RNAseq analysis-DNA methylation analyses through both arrays and methylation-specific NGS-Integrative Genomic analyses such as QTLs, Mendelian Randomization, TWAS, Bayesian approaches… However we are flexible with the profile of the candidate and will prioritize highly motivated applications with genuine interest in (Epi)Genomics. We offer the possibility to apply to the call with us (with a moderate-high probability of success, we hope). The call would include a one-three year contract to work at our lab, in a friendly, motivating environment and with a salary of around 36,000€ per annum. This would translate into around 14 pays of 2,000-2,200€ with total health coverage, insurances and so on, and a moving allowance of 3,500€, which is a good salary to live in Spain. Candidates must have more than 24 months of postdoctoral experience outside Spain, regardless of the country of origin.
The Spatial-Cell-ID facility of Lyon is seeking highly qualified personnel for the following positions:
● a bioinformatician/computational biologist specialized in spatial transcriptomics. The successful candidate will lead the development of methods and pipelines to analyse biological data generated. ● a biophysicist/bioengineer specialized in instrumentation for targeted spatial transcriptomics. The successful candidate will set up a multi-user imaging platform dedicated to spatial transcriptomics on multiple types of biological samples.
Spatial-Cell-ID is a new national spatial transcriptomics facility funded by the French “EquipEx+” excellence initiative and led by the École Normale Supérieure of Lyon (ENSL). It aims to study cellular identity and its spatial heterogeneity within tissues, organs, or biological systems in normal and pathological contexts, through very recent developments in spatial transcriptomics. Spatial transcriptomics technologies were elected “Method of the Year 2020” by the Nature Methods journal and are currently revolutionizing our ability to study complex biological systems. Spatial-Cell-ID offers national equipment for spatial transcriptomics that integrates imaging, sequencing, and data analysis technologies which in synergy will provide access to the transcriptome of any single cell within its native spatio-temporal environment. It hosts a comprehensible selection of technologies, including single-cell transcriptomics (10x Genomics), untargeted spatial transcriptomics (e.g., Slide-seq), and targeted spatial transcriptomics (e.g., MERFISH), associating state-of-the-art technological platforms of the University of Lyon. The data analysis hub of Spatial-Cell-ID will be located at the École Normale Supérieure of Lyon.
The employer : The École Normale Supérieure de Lyon is an elite French public higher education institution that trains professors, researchers, senior civil servants as well as business and political leaders. It is a symbol of French Republican meritocracy and it remains committed today to disseminating knowledge to the widest audience and to promoting equal opportunity. The ENSL brings together several laboratories at the cutting edge of science and working on different fields of Biology, Mathematics, Physics and Humanities.
Bioinformatician/computational biologist :
The appointed candidate will coordinate the data analysis hub of Spatial-Cell-ID and assist the users in the analysis of their single cell and spatial data. She/he will be working at the ENS of Lyon and closely collaborate with biologists and bioinformaticians to implement data analysis pipelines and develop new procedures as needed. She/he will communicate findings, coordinate skill transfers between labs, and provide training to project members as needed. She/he will be provided with extensive computational resources (workstations, High Performance Computing facility of the ENS de Lyon) and will benefit from the support of the bioinformatics community within Spatial-Cell-ID.
Profile : ● PhD or equivalent experience in quantitative science (Bioinformatics, Computational Biology etc.). ● Good knowledge of one or more programming/scripting languages (e.g. Python, R, bash). ● Experience in omics data analysis, ideally in the context of single-cell and spatial technologies. ● Experience or the aptitude to quickly become proficient with the following techniques: untargeted spatial transcriptomics (e.g. Visium, Slide-Seq), targeted spatial transcriptomics (e.g. MERFISH), image analysis, machine learning methods for the analysis of biological data. ● Excellent communication and collaboration skills. English is the working language.
Desired starting date : Between October 2021 and January 2022. Contract duration : 3 years, renewable. The position might lead to a permanent post. Salary : Remuneration based on experience (from 2000€/month for a junior to 3000€/month for a senior research engineer).
Instructions for applicants : Applications should include a CV, a cover letter, and contact details for 3 referees to be sent to: Yad Ghavi-Helm (yad.ghavi-helm@ens-lyon.fr). Please use the email subject “Spatial Cell ID”. For further information please contact the same address. Applications will be considered upon submission.
Biophysicist/bioengineer :
The appointed candidate will build the imaging platform for targeted spatial transcriptomics of Spatial-Cell-ID. He/she will design, set up and interface the different parts of the experiment: microfluidic controls, super-resolution confocal imaging and acquisition system. Once the experimental setup is running, he/she will assist new users and train them when needed. The recruited engineer will be working at the ENS of Lyon and closely collaborate with biologists, microscopists and biophysicists, who will assist him/her in the different aspects of this highly interdisciplinary project.
Profile : ● Master’s or Engineering degree in biophysics/bioengineering/biology is required. ● Strong interest in instrumentation, if possible with experience in visual programming and coding for interfacing. ● Experience or the aptitude to quickly become proficient with the different steps involved in spatial transcriptomics experiments: design of probes, smFISH experiments, image acquisition and analysis. ● Excellent communication and collaboration skills. English is the working language. ● Experience in imaging of biological systems and/or microfluidics is a plus.
Desired starting date : January 2022 Contract duration : 3 years. Salary : Remuneration based on experience (from 2000€/month for a junior to 3000€/month for a senior research engineer). Instructions for applicants : Applications should include a CV, a cover letter, and contact details for 3 referees to be sent to: Jonathan Enriquez (jonathan.enriquez@ens-lyon.fr) & Sigolène Lecuyer (sigolene.lecuyer@ens-lyon.fr). Please use the email subject “Spatial Cell ID”. For further information please contact the same addresses. Applications will be considered upon submission.
The Telethon Institute of Genetics and Medicine (TIGEM) is part of the newly formed School for Advanced studies (SSM) and hosts a program in Genomic ad Experimental Medicine for undergraduate and graduate students and postdoctoral fellows/researchers in early stages of their professional careers. For the latter category a call for three positions has just been released.
A full-time position at the Lee Kong Chian School is Medicine is open for an Assistant Professor of Metabolic / Nutrition / Microbiome Medicine. Reporting to the Dean and Vice Dean, Research, the appointee is expected to undertake high quality research in Metabolic/ Nutrition/ Microbiome Medicine, in line with the research strategy of the School. The appointee will obtain research funding and supervise research staff and students. The appointee is also expected to undertake teaching and educational responsibilities for the training of medical students and postgraduate research students.
Person Specification:
MBBS/MD and/or PhD
Relevant postdoctoral experience
Significant experience and outstanding, record of translational clinical research and teaching with a high level of scientific achievement, productivity and impact in the field of Metabolic/ Nutrition/ Microbiome Medicine
Ability to supervise research staff and students
Good communication skills and an appreciation for constructive teamwork
Willing to participate in postgraduate and undergraduate education and training
Experience and desire to participate in postgraduate and undergraduate education and training
Track record of having supervised graduate students to successful completion of PhDs
UNIL is a leading international teaching and research institution, with over 5,000 employees and 17,000 students split between its Dorigny campus, CHUV and Epalinges. As an employer, UNIL encourages excellence, individual recognition and responsibility.
Presentation
We are looking for a passionate and creative scientist who will actively participate in the development, coordination and follow up of the research activities in the group of Prof. Liliane Michalik at the CIG (Center for Integrative Genomics) of the University of Lausanne.
Job information
Expected start date in position : 01.10.2021 or to be agreed Contract length : 1 year, renewable maximum 4 years Activity rate : 50%-60% Workplace : University of Lausanne, Dorigny
Your responsibilities
You will become acquainted with the field of skin responses to injuries. You will design and conduct experiments as part of ongoing research projects in the laboratory. You will interpret and communicate results. You will keep up to date with the literature. You will prepare, write and publish research articles. You will be in charge of following up on research and you will assist the PI in the coordination of the laboratory activities.
Your qualifications
PhD or MD-PhD degree in life sciences. The ideal candidate will be highly motivated and team player; will have the ability to work independently with strong work ethic and critical thinking; will have experience in cell culture, RNA and protein extraction, RT-PCR; will have excellent communication and organization skills. She/he will be fluent in English and will have excellent writing skills in French and English. Previous experience in working with mice is a plus, but not mandatory.
What the position offers you
The Michalik’s lab is hosted at the Center for Integrative Genomics (CIG) at the University of Lausanne (UNIL), a well-funded institute with a focus on functional genomics and equipped with modern core facilities (see www.unil.ch/cig). It is embedded in the broader Lausanne research environment that includes two universities (UNIL, EPFL), the Swiss Institute of Bioinformatics, Ludwig Center for Cancer Research, university hospital, and a cluster of biotech companies flourishing in the larger lake Geneva area. Lab members benefit from networking and training opportunities.
Deadline : 09.07.2021 Please submit a motivation letter, a full CV, list of your scientific publications, statement of research interests, copies of your diplomas (especially of your PhD degree) and contact details for 2 or more referees. Only applications through this website will be taken into account. We thank you for your understanding.
