Source

Centre for Investigation and Research in Sleep (CIRS), Lausanne University Hospital (CHUV), 1011 Lausanne, Switzerland.

Abstract

BACKGROUND:

Positional therapy that prevents patients from sleeping supine has been used for many years to manage positional obstructive sleep apnea (OSA). However, patients’ usage at home and the long term efficacy of this therapy have never been objectively assessed.

METHODS:

Sixteen patients with positional OSA who refused or could not tolerate continuous positive airway pressure (CPAP) were enrolled after a test night study (T0) to test the efficacy of the positional therapy device. The patients who had a successful test night were instructed to use the device every night for threemonths. Nightly usage was monitored by an actigraphic recorder placed inside the positional device. A follow-up night study (T3) was performed after threemonths of positional therapy.

RESULTS:

Patients used the device on average 73.7±29.3% (mean±SD) of the nights for 8.0±2.0h/night. 10/16 patients used the device more than 80% of the nights. Compared to the baseline (diagnostic) night, mean apnea-hypopnea index (AHI) decreased from 26.7±17.5 to 6.0±3.4 with the positional device (p<0.0001) during T0 night. Oxygen desaturation (3%) index also fell from 18.4±11.1 to 7.1±5.7 (p=0.001). Time spent supine fell from 42.8±26.2% to 5.8±7.2% (p<0.0001). At threemonths (T3), the benefits persisted with no difference in AHI (p=0.58) or in time spent supine (p=0.98) compared to T0 night. The Epworth sleepiness scale showed a significant decrease from 9.4±4.5 to 6.6±4.7 (p=0.02) after threemonths.

CONCLUSIONS:

Selected patients with positional OSA can be effectively treated by a positional therapy with an objective compliance of 73.7% of the nights and a persistent efficacy after threemonths.

Copyright © 2011 Elsevier B.V. All rights reserved.