The FBM has published a recap of all core facilities available at the UNIL.
Read about our close neighbours below, and about the full list here:
Cellular Imaging Facility CIF
Electron Microscopy Facility EMF
Dubochet Center for Imaging DCI (UNIL platform)
Flow Cytometry Facility FCF
In Vivo Imaging Facility IVIF
Cardiovascular Assessment Facility CAF
Histology Facility HF
Protein Analysis Facility PAF
Metabolomics & Lipidomics Facility MLF
Bioinformatics Competence Center BICC
Biostatistics Facility BSF
Genomic Technologies Facility GTF
Clinical Research Center CRC
BIOINFORMATICS COMPETENCE CENTER BI CC
The Bioinformatics Competence Center (BI C) is run jointly by FBM and EPFL’s School of Life Sciences. It provides highly specialized
resources in bioinformatics for all aspects of data processing and analysis. Experts at the BI Ɔ C provide customized data analysis services
that go beyond standard protocols to include project-specific algorithms, data processing pipelines, web reporting systems and
visualization tools. The BI C is currently working on a wide range of projects: bulk and single-cell RNAseq data analysis, alternative
splicing, ChipSeq, ATAC-Seq, Hi-C, DNA methylation, genome assembly, flow and mass cytometry data analysis, the detection of
mutations in tumors, the prediction of mutation effects on proteins, proteomic, lipidomic and metabolomic analyses, and data
formatting, aggregation and presentation (such as on customized websites).
The BI C is intended for use by researchers at FBM, other UNIL faculties, EPFL, and outside entities (including companies, based on specific
BIOSTATISTICS FACILITY BSF
The Biostatistics Facility (BSF) supports researchers with all aspects of biostatistics, including the analysis of data from high-throughput
sequencing and the power analyses needed to prepare animal-testing requests. The BSF offers consulting services for all research steps
requiring biostatistics: experimental design, writing grant applications, running the analyses and communicating the results. Its experts
provide different forms of training such as courses, workshops, and tailored programs on specific statistical procedures for individual labs.
The BSF is intended for use by researchers at FBM, other UNIL faculties and outside entities (including companies, based on specific
CELLULAR IMAGING FACILITY CIF
The Cellular Imaging Facility (CIF) provides a wide range of optical microscopy services along with training (through courses, workshops
and video tutorials) and consulting on topics such as using the latest open-access systems and developing tailor-made data acquisition
and analysis protocols. Facility staff are available to support scientists in their research. The CIF is spread across four sites – Agora, Bugnon,
Dorigny and Epalinges – each possessing a variety of imaging instruments for both general and specific research needs. In response to
growing demand for remote access, the facility has set up powerful data processing and analysis workstations that can be used remotely
for tasks like deconvolution and 3D reconstruction and for running common imaging software.
The CIF is intended for use by researchers at FBM, other UNIL faculties and outside entities (including companies, based on specific
DUBOCHET CENTER FOR IMAGING DCI
The Dubochet Center for Imaging (DCI), managed jointly by UNIL, École polytechnique fédérale de Lausanne (EPFL) and the University of
Geneva (UNIGE), is highly specialized in cryo-electron microscopy. It is named after Prof. Jacques Dubochet, who was awarded the 2017
Nobel Prize in Chemistry for his pioneering work in cryo-EM technology. The DCI aims to firmly establish the Lake Geneva region as a
center of excellence in bioimaging research.
The sophisticated technology available at the DCI lets researchers address questions related to single particle analysis, visualize structures
at the atomic level and use cryo-electron tomography to observe single molecules in their cellular context.
The DCI provides support to biomedical researchers by offering state-of-the-art equipment along with the expertise of a specialized team
to perform the entire structural analysis pipeline. In addition, the DCI’s experts work to strengthen bridges with methods such as light
microscopy and FIB-SEM, and to extend cryo-EM to smaller and more flexible particles.
The DCI is intended for use by researchers at UNIL, EPFL, UNIGE and outside entities (including companies, based on specific agreements).
The DCI is a simple partnership under the authority of the UNIL rectorate and not of the FBM. Therefore, the DCI is not a faculty platform of the FBM and is in
no way bound by agreements concluded between UNIL and external partners regarding the access to or running of the faculty platforms/facilities of the FBM.
GENOMIC TECHNOLOGIES FACILITY GTF
The Genomic Technologies Facility (GTF) mission is to provide access to state-of-the-art instruments, methods and support for measuring
quantitative and qualitative variations in nucleic acids. Its experts are skilled in leading-edge genomics technology with a wide range of
analytical applications. The GTF also offers ad hoc bioinformatics support and dedicated computing and storage infrastructure. It has
the genomics expertise to help researchers choose the most appropriate technology for their research aims, improve their experimental
design, run wet lab experiments, sequence libraries, perform primary data and biostatistical analyses, and manage data distribution.
The GTF is intended for use by researchers at FBM, other UNIL faculties and outside entities (including companies, based on specific
PROTEIN ANALYSIS FACILITY PAF
The Protein Analysis Facility (PAF) runs analyses of single proteins and proteomes. It employs advanced mass spectrometry methods to
identify and quantify a large fraction of the proteins expressed in cells, tissues and organisms. The PAF also conducts large-scale profiling
of post-translational modifications (e.g., phosphoproteome and ubiquitinome) using these same methods. Other common applications
include the identification of protein-protein interactions and the study of proteomes of subcellular compartments. PAF staff provide
comprehensive support at all stages, from experiment planning and sample preparation to data analysis. They also carry out fast, sensitive
quantification of selected targets by capillary western assays as a complement to mass-spectrometry-based untargeted assays.
The PAF is intended for use by researchers at FBM, other UNIL faculties and outside entities (including companies, based on specific