For one of our clients, a fast growing Biotherapeutics company located at the Biopole (Lausanne), we are looking for a:

PRINCIPAL SCIENTIST
CELLULAR IMMUNOLOGY & ASSAY DEVELOPMENT

ROLE OVERVIEW:
To lead validation of novel biological targets, performing and analyzing experiments in the field of immune- oncology and autoimmune diseases to deliver the next wave of novel therapeutic concepts. We are looking for an experienced, independent and flexible team player.

RESPONSIBILITIES:

• Lead the identification and validation of new therapeutic concepts to build the portfolio in immuno- oncology and autoimmune diseases.
• Lead, develop, perform and analyze immunological assays including but not limited to immuno- oncology assays such as immune profiling using multi-color flow cytometry, multiplex cytokine profiling, gene expression profiling, ELISA, binding assays and functional primary human cell-based assays for the characterization of novel biological candidates.
• Perform cell culture, including primary human cultures, development and maintenance of cell lines.
• Contribute to inter-disciplinary research efforts in a cross-functional setting.
• Design, perform and analyze experiments and communicate results in a timely manner.
• Maintain experimental records in electronic laboratory notebook format.
• Review relevant scientific literature, experimental design, troubleshooting, analysis and interpretation of data
• Assist with general laboratory duties including lab equipment maintenance, ordering and receiving of lab supplies.
• Lead external collaborations to build the portfolio as needed
• Comply with all safety guidelines
• Perform other relevant responsibilities as required.
• Manage a small team of direct reports

REQUIREMENTS:

• PhD (entry level) or Master’s degree in immunology, cellular biology or related life sciences with at least 5 years of experience in drug discovery
• Solid and demonstrable bench level experience in the development, validation and implementation of immunological assays
• Hands-on expertise in methodologies, reagents and instruments used for primary cell cultures, flow cytometry (mandatory), ELISA and cytokine analyses
• Experience with handling primary cells in BSL-2 level facilities, isolation of immune cells from human biological samples (PBMC) is mandatory. Practical knowledge in data analysis using standard software (e.g. Excel, GraphPad, JMP, Flow cytometry dedicated software)
• Experience in antibody discovery and pharmaceutical industry is a plus
• Excellent written and verbal communication skills in English; proficiency in French is a plus
• Strong organizational skills with the capacity to handle multiple tasks simultaneously
• Ability to work independently as well as part of a cross-functional team
• Strong interpersonal communication skills
• Excellent lab management skills and mentoring skills
• Strong work ethic and willingness to participate in a fast-paced work environment

Any question? Please call Joanna Jones, Head of recruitment: +41 78 619 76 70

Interested? Please apply by e-mail: recruitment@consultantsinscience.com

Consultants in Science
Biopole SC-A
Route de la Corniche 4
CH – 1066 Epalinges