Seminars & Workshops Archive

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PhyloSIB 2020: the Swiss meeting on phylogenetics – Wed. Jan 29 2020, GEN, Aud. A

PhyloSIB is an annual workshop with an emphasis on molecular evolution, phylogenetics and comparative phylogenomics.

Invited international speakers: Olivier Gascuel (Pasteur), Paul Thomas (University of Southern California)

The goal of PhyloSIB is the exchange of knowledge and the discussion of current studies and recent developments in phylogeny. Participants are typically developers of analysis tools, authors of databases, expert users and students on their way there. The meeting typically brings together around 40 persons from all across Switzerland.

These year’s PhyloSIB is hosted by the UNIL Department of Computational Biology.

Initiated in 2006 and organised many years by Brigitte Boeckmann from the Swiss-Prot group, the full-day meeting has been under the stewardship of the Swiss-Orthology group in recent years.

Registration (free, but required for coffees and lunch): https://doodle.com/poll/4dvrsu953fzttgxr
Full schedule (still subject to change): http://bit.ly/PhyloSIB

Organisers: 

  • Damian Szklarczyk (UZH)
  • Evgenia Kriventseva (UNIGE)
  • Christophe Dessimoz (UNIL)

 

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CIG Symposium 2020: Registration is now open!

 

Link to the CIG Symposium website

Link to the online registration form (sign in after registration in order to submit your abstract by May 15, 2020!)

Link to the program

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Mon Jan 27, 2020 CIG Sem. D. Wagner

CIG Seminars Spring 2020

Monday 12:15, Génopode, auditorium B, followed by pizza for registered PhD students & postdocs

Free entrance

Download the poster

Monday January 27, 2020
Doris Wagner, University of Pennsylvania, USA
«(Re)programming cell fate and function in the context of chromatin»
Host: Christian Fankhauser

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CIG-DNF joint seminar: Prof. Frank Kooy, DNF Aud., Bugnon 7-9, Jan. 28, 2020

Abstract: Many pathways have been involved in pathophysiology of the fragile X syndrome, one of the more frequent genetic causes of intellectual disability and autism. This review highlights the recent insights in the role the abnormalities in the GABAergic system play in the disorder. Since the initial observations made that the expression of specific subunits of the GABA(A) receptor were underexpressed in the fragile X knockout mouse model more than a decade ago, evidence has accumulated that the expression of approximately half of the GABAergic system is compromised in multiple species, including in fragile X patients. Functional consequences of the GABAergic deficiencies could be measured using whole-cell voltage clamp recordings. In an in vitro model of  cortical microcircuitry we observed that the loss of FMRP largely affected the electrophysiological   correlates  of  network  development  and  maturation  but  caused  less  alterations  in  single  –  cell   phenotypes Pharmalogical treatment with agonist of the receptor was been able to restore several behavioral deficits in the fragile X mouse model, including seizures, marble burying and, in part, prepulse inhibition. Trials in patients with the same agonist have demonstrated encouraging post-hoc results in the most severely affected patients, although no effect could be demonstrated in the patient group as a whole.. In conclusion, there can be little doubt that the GABAergic system is compromised in the fragile X syndrome, but also in other neurodevelopmental disorders,  and that these abnormalities contribute to the clinical abnormalities observed.

 

You can access the DNF using public transportation. If you arrive by car, as we have no available parking places on site (Bugnon 7-9), please find a parking place at the Hospital parking or in a blue parking zone along the road.

 

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Mon Feb 10-Tues Feb 11, 2020 – Lausanne Genomics Days 2020

Lausanne Genomics Days 2020

is an annual event sponsored by the University of Lausanne and the Conférence Universitaire de Suisse Occidentale (CUSO). This 2-day event will bring to Lausanne investigators from Europe and the United States to present and discuss the newest developments in genomics and genomic technologies and their impact on biological research.

Download the flyer

Monday & Tuesday February 10  & 11, 2020

Génopode, Aud. C

Registration

Preliminary Program (with webpage links)

 

Monday February 10th

 

09:30-10:00 Welcome and coffee in the Génopode hall

 

10:00-11:45 Translation regulation session

Session’s chaiperson

Prof. Sven Bergmann

 

Keynote presentation speaker

10:00 Prof. Tamir Tuller

Computational deciphering and modelling of novel gene expression rules encoded in the mRNA

 

Local speakers

10:45 Dr. Anneke Brümmer (Prof. Sven Bergman group)

LincRNA sequences are biased to counteract their translation

11:00 Dr. Cedric Gobet (Prof. Felix Naef lab)

Modeling ribosome dwell times and relationships with aminoacyl-tRNAs in mouse liver

11:25 Prof. David Gatfield

Transcriptome-wide sites of collided ribosomes reveal sequence determinants of translational pausing

 

11:45-13:00 Lunch in the Génopode hall

 

13:00-14:45 RNA processing session

Session’s chaiperson

Dr. Julien Marquis

 

Keynote presentation speaker

13:00 Prof. Stefan Ameres

SLAMseq – Dissecting gene regulatory mechanisms by time-resolved RNA sequencing

 

Local speakers

13:45 Dr. Flora Brozzi (Prof. Romano Regazzi lab)

RNA-tagging to unveil beta-cell/immune cell crosstalk in diabetes pathogenesis

14:05 Dr. Rodrigo Siqueira Reis (Prof. Yves Poirier lab)

Complex mRNA-antisense lncRNA interaction revealed by SHAPE-MaP

14:25 Lina Worpenberg (Prof. Jean Yves Roignant lab)

Shaping the nervous system by m6A mRNA modification

 

14:45-15:15 Coffee break in the Génopode hall

 

15:15-16:55 Gene editing session

Session’s chaiperson

Prof. Julia Santiago Cuellar

Keynote presentation speaker

15:15 Prof. Martin Jinek

Molecular mechanisms of genome editors

 

Local speakers

15:55 Dr. Robertas Ursache (Prof. Niko Geldner lab)

CRISPR and the new age of genetic analysis in Arabidopsis

16:20 Dr. Lotte Spel (Prof. Fabio Martinon lab)

Understanding molecular mechanisms in autoinflammation using CRISPR screens

 

16:45 Apéro in the Génopode hall

 

Tuesday February 11th

09:30-10:00 Welcome and coffee in the Génopode hall

 

10:00-11:45 Microbiome analysis session

Session’s chaiperson

Prof. Philipp Engel

 

Keynote presentation speaker

10:00 Prof. Colin Hill

A voyage through the gut virome

 

Local speakers

10:45 Dr. Kirsten Ellegaard (Prof. Philipp Engel lab)

Getting quantitative on the Microbiome: vast differences in strain-level diversity among host-associated bacterial communities

11:05 Paddy Gibson (Prof. Jan-Willem Veening lab)

Deciphering the origins of amoxicillin resistance in Streptococcus pneumoniae through experimental evolution and NGS

11:25 Prof. Guillem Salazar Guiral

Disentangling the effects of gene expression changes and community turnover in the global ocean

 

11:45-13:30 Lunch in the Génopode hall

 

13:30-15:15 Evolution Session

Session’s chaiperson

Prof. Tanja Schwander

 

Local speakers

13:30 Prof. Anne Roulin

Transposable element evolution in small genomes What can we learn from population genomics in B. distachyon?

13:50 Jelisaveta Djordjevic

Sexual conflict and the ontogeny of sex-biased gene expression in stick insects

14:10 Tom Kay

Position in the social network is a central driver of behavior and gene expression in ants

 

Keynote presentation speaker

14:30 Prof Detlev Arendt

Evolution of neurons and of the nervous system

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CIG Seminars Spring 2020 Program

CIG Seminars Spring 2020

Monday 12:15, Génopode, auditorium B, followed by pizza for registered PhD students & postdocs

Free entrance

Download the poster

Monday January 27, 2020
Doris Wagner, University of Pennsylvania, USA
«(Re)programming cell fate and function in the context of chromatin»
Host: Christian Fankhauser

Monday February 24, 2020
Emi Nagoshi, University of Geneva, Switzerland
«Circadian regulation of sleep in Drosophila»
Host: Richard Benton

Monday March 16, 2020
Benedetta Bolognesi, Centre for Genomic Regulation, Barcelona, Spain
«Understanding disordered protein regions by deep mutagenesis»
Host: Jolanda van Leeuwen

Monday March 30, 2020
Schraga Schwartz, Weizmann Institute of Science, Rehovot, Israel
«TBA»
Host: Jean-Yves Roignant

Monday April 27, 2020
Dagmar Kratky, University of Graz, Austria
«Consequences of defective lipolysis: Lessons from mutant mouse models»
Host: Lluis Fajas Coll

Monday May 11, 2020
Maria (Charo) Robles, Ludwig-Maximilians-Universität  München, Germany
«Using proteomics to study daily dynamics of physiology»
Hosts: PhD students & Postdocs

Monday May 18, 2020
Suliana Manley, EPFL, Lausanne, Switzerland
«High-throughput super-resolution microscopy reveals organelle structure and dynamics»
Host: Maria C. Gambetta

Monday June 29, 2020
Herwig Baier, Max Planck Institute of Neurobiology, Martinsried, Germany
«Vision to action in the zebrafish brain»
Host: Thomas Auer